The oligomeric form of Amyloid Beta peptide (AB, 1-42) has been closely linked to Alzheimers Disease. Several ELISAs targeting AB have been developed; however, these ELISAs are known to cross-react with Amyloid Beta precursor protein (APP) and are poorly characterized against monomeric and oligomeric forms of the peptide. The Biosensis MOAB-2 antibody, developed by LaDu and co-workers (Youmans K. et al., 2012), has been shown to specifically detect AB, but not the precursor molecule APP. When utilized in ELISAs, the oligomeric form of AB peptide (o-AB) can be assayed independently of the other forms of the molecule when assayed with the MOAB-2 monoclonal antibody.
产品特点
该ELIAS试剂盒包含:2 x 96孔预包被条孔板(可拆卸), protein standards, QC sample, detection reagents, wash and sample buffers, substrate buffer and detailed protocols.