Furin is a ubiquitous protein located within the trans-Golgi network. It is found in many tissues and cell lines including MDCK,HeLa,HepG2 and NIH-3T3. Furin is a proprotein convertase that is responsible for the proteolytic maturation of many precursor proteins that are secreted from the constitutive secretory pathway
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~95-110 kDa Furin/PACE. A splice variant (~60 kDa) can also be detected.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 779 of mouse Furin/PACE
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠、牛、绵羊种属来源的Furin/PACE蛋白发生免疫反应.
保存建议
提供的Furin/PACE抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该Furin/PACE抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.