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中文名称

Lissamine-rhodamine B-十二烷酰基-半乳糖基神经酰胺

英文名字
Lissamine-rhodamine B-dodecanoyl-galactosylceramide
供应商
Matreya
产品货号
2204-500
产品报价
¥询价/500ug
产品说明书
购买方式
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产品新闻
背景资料
Lissamine-rhodamine B-dodecanoyl-galactosylceramide is a fluorescent labeled glycosphingolipid containing a galactose attached to a ceramide and labeled with a fluorescent lissamine-rhodamine B marker. This fluorescent standard from Matreya is excellent for use in the identification and isolation of cerebrosides in the Krabbe’s disease and other studies.3 Lissamine-rhodamine B dyes have an excitation/emission maxima ~560/580 nm. The fluorescent marker is attached via a 12-carbon linker reducing the interaction of the fluorophore with the sphingolipid. Galactosylcerebrosides are found primarily in neuronal tissues and are a major component of the central nervous system. They are the largest single component of the myelin sheath of nerves and seem to act, along with other molecules, to form part of the structural support of the myelin sheath.1 Cerebrosides are involved in a very wide range of biological activities such as cell agglutination, intracellular communication, cellular development, and antitumor/cytotoxic effects.2 Galactocerebroside can be metabolized into sulfatide which is also abundant in the nervous system and myelin sheath. Due to the relatively high melting point of cerebrosides (much greater than physiological body temperature) they have a paracrystalline structure. Krabbe’s disease (globoid cell leukodystrophy) is characterized by a deficiency in the enzyme galactocerebrosidase, which is responsible for degrading galactocerebroside. This leads to an accumulation of cerebroside and psychosine which can result in demyelination of nerves and loss of axonal conductivity.
产品描述
Sulforhodamine B-C12.0 cerebroside
产品形式
该Lissamine-rhodamine B-十二烷酰基-半乳糖基神经酰胺产品为固体形式
保存建议
对于本产品,我们推荐使用-20℃蓝冰低温进行运输。在您收到货物后,我们建议在-20℃温度下冷冻保存,溶解使用说明请参考本品说明书。
其他
Matreya LLC是一家脂质生化公司,致力于开发和制造高质量的脂质和生物化学品。Matreya在化学合成以及天然产物提取和纯化方面经验丰富,生产出的产品具有最佳纯度。 Matreya产品线包括一系列鞘脂、糖脂、鞘糖脂、脂肪酸和酯、甾醇和维生素E异构体(生育酚和生育三烯酚)。专长是生产高纯度鞘氨醇、神经酰胺、硫酸酯、神经节苷脂、酶抑制剂、生育酚和生育三烯酚。是全球提供脂质产品最全的供应商之一。产品涉及生物化学、制药、微生物学、食品和农业等研究领域。
注意
该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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